lacking rest, lacking calmness (see Molina; he has put this in the first person singular, I am lacking rest, I am not calm)
Alonso de Molina:
acan ninotlalia. no tener reposo ni sosiego. Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 1v. col. 2. Thanks to Joe Campbell for providing the transcription.