a plant published in 1552 as having healing properties, this plant is apparently part of the tobacco family, and it is listed as a psychoactive drug in Jan G.R. Elferink, Journal of Psychoactive Drugs, 20:4 (1988), 427-435.
See an image that represents aquiztli in the Visual Lexicon of Aztec Hieroglyphs, ed. Stephanie Wood (Eugene, Ore.: Wired Humanities, 2020-present).
The Florentine Codex describes it and provides an illustration of the plant, which is said to have medicinal use when drunk as an infusion in bringing blisters to the surface. It is "drunk uncooked when fasting." But it is also something that burns and causes blisters.