huei altepetl.

Headword: 
huei altepetl.
Principal English Translation: 

city, large town or ethnic state (see Molina)

Orthographic Variants: 
uei altepetl, huey altepetl
Alonso de Molina: 

uei altepetl. ciudad.
Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 155v. col. 1. Thanks to Joe Campbell for providing the transcription.

Attestations from sources in English: 

"And Coyoacan is also at times called huey altepetl (great, large altepetl), as is characteristic of complex altepetl elsewhere in central Mexico."
Rebecca Horn, Postconquest Coyoacan: Nahua-Spanish Relations in Central Mexico, 1519-1650 (1997), 37.

"There are the big cities or huey altepetl ciudades of Aztlan (1-9-46), Amaquemecan (1-86-11), Mexico Tenochtitlan (11-22-47), Burgos (1-177-25), Plasencia (1-177-46), and Granada (1-177-51)." Several additional huey altepetl are also attested in Chimalpahin's works, such as Vienna, Cairo, Tula, Babylon, Genoa, Rome, Salamanca, Tetzcoco, and Madrid. His world view is strinkingly focused on Mexico, Spain, and Italy, but even Egypt enters into it.
See Susan Schroeder, Chimalpahin and the Kingdom of Chalco (1991), 120.

"[T]he king of the dominant city was called huey tlatoani, great king, and his city was a huey altepetl, great city."
Pedro Carrasco, The Tenochca Empire of Ancient Mexico (2012), 423.

"Most clearly there is the prehispanic namesign of Cholula, or more precisely Tollan Cholula, designated on the map as great altepetl (huey altepetl), obviously meant to designate the entire province of Cholula."
Ton Salman and ‎Anke van Dam, The Legacy of the Disinherited (1997), 82.

"As to the famed and mysterious place of origin of the Aztecs, there is a mention of the "great water mirror that surrounds the great city of Aztlan" (huey atezcatl yn quiyahuallotoc huey altepetl aztlan) (Chimalpahin 1 99 1 , 26-27)."
Guilhem Olivier, Mockeries and Metamorphoses of an Aztec God (2003), 260.

Attestations from sources in Spanish: 

"En lo que respecta al huey altepetl sólo he encontrado hasta ahora una referencia: Torquemada, Monarquía, vol. IV, libro XIV, cap. VTI: 332. 'El modo que estas gentes indianas tenían de repartir el suelo de toda la tierra era de esta...'"
Andrea Martínez Baracs, Un Gobierno de Indios: Tlaxcala, 1519-1750 (2008), 99.

Huey Altepetl Tlaxcallān = señorío de Tlaxcala
https://es.wikipedia.org/wiki/Se%C3%B1or%C3%ADo_de_Tlaxcala_(Huey_Altepetl_Tlaxcall%C4%81n)