Principal English Translation: 

beside, next to; the corner; in the ears; also: -nacazco and -nacaztlan, postpositions or suffixes found in place names

Orthographic Variants: 
Alonso de Molina: 

nacazco. to. enlas orejas.
Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 062r. col. 1. Thanks to Joe Campbell for providing the transcription.

Attestations from sources in English: 

yc nohuiyan cacalnacasco = at house corners everywhere
Here in This Year: Seventeenth-Century Nahuatl Annals of the Tlaxcala-Puebla Valley, ed. and transl. Camilla Townsend, with an essay by James Lockhart (Stanford: Stanford University Press, 2010), 128–129.

hoquinanacaztatacac (also seen as hoquinanacaztatac) = dug in the corners
S.L. Cline. Colonial Culhuacan, 1580–1600: The Social History of an Aztec Town, 190. Copyright 2002 by Sarah Cline. All rights reserved.]