Principal English Translation: 

to be happy, content; or, to be healthy
James Lockhart, Nahuatl as Written: Lessons in Older Written Nahuatl, with Copious Examples and Texts (Stanford: Stanford University Press and UCLA Latin American Studies, 2001), 229.

Alonso de Molina: 

pactinemi. ni. (pret. onipactinenca vel. onipactinemia.) tener salud, o andar alegre y contento.
Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 79r. col. 1. Thanks to Joe Campbell for providing the transcription.

Lockhart’s Nahuatl as Written: 

ni. Class 2 irregular: ōnipāctinenca. pāqui, nemi. 229