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poyomahtli.

Headword: 
poyomahtli.
Principal English Translation: 

a narcotic, a hallucinogen (see Bierhorst, attestations)

Orthographic Variants: 
poyomatli
Attestations from sources in English: 

aromatic preparation mixed with stimulating drugs, whether smoked or drunk
Gran Diccionario Náhuatl, citing Wimmer 2004, https://gdn.iib.unam.mx/diccionario/poyomatli/60560