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chacayulli.

Headword: 
chacayulli.
Principal English Translation: 

calluses on the feet or hands

Alonso de Molina: 

chacayulli. callos delos pies, o delas manos.
Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 18v. col. 2. Thanks to Joe Campbell for providing the transcription.