carelessness, sluggishness, or negligence (see Molina)
Alonso de Molina:
cuitlazcopicyotl. descuydo, floxedad, o negligencia. Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 27v. col. 2. Thanks to Joe Campbell for providing the transcription.