ixpopoyoti.

Headword: 
ixpopoyoti.
Principal English Translation: 

to go blind

IPAspelling: 
iːʃpopoyoːti
Alonso de Molina: 

ixpopoyoti. n. (pret. onixpopoyot.) cegar.
Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 47r. col. 1. Thanks to Joe Campbell for providing the transcription.

Frances Karttunen: 

ĪXPOPOYŌT(I) to go blind / cegar (M) [(2)Cf.57V. R has this with a short vowel and glottal stop in the fourth syllable instead of a long vowel. See ĪXPOPOYŌ-TL
Frances Karttunen, An Analytical Dictionary of Nahuatl (Norman: University of Oklahoma Press, 1992), 118.

Attestations from sources in English: 

aço teucocoliztli itech motlaliaya aço ixpopoiutia anoço quexilivia = Either leprosy settled on him, or he went blind, or the groin was disordered
Fray Bernardino de Sahagún, Primeros Memoriales, ed. Thelma D. Sullivan, et al. (Norman: University of Oklahoma Press, 1997), 167.

aocmo tle yc pati = There is nothing by which it is cured (central Mexico, sixteenth century)
Fray Bernardino de Sahagún, Primeros Memoriales, ed. Thelma D. Sullivan, et al. (Norman: University of Oklahoma Press, 1997), 285.