to be scandalous, or to become very blind to what is very much clear (reality) (see Molina)
Orthographic Variants:
ixtlayoua
IPAspelling:
iːʃtɬɑjowɑ
Alonso de Molina:
ixtlayoua. n. (pret. onixtlayouac.) encandilarse, o cegarse con la mucha claridad. Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 48r. col. 1. Thanks to Joe Campbell for providing the transcription.