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ixxoxohuia.

Headword: 
ixxoxohuia.
Principal English Translation: 

to appear pale, discolored due to an illness (see Molina)

Orthographic Variants: 
ixxoxouia
Alonso de Molina: 

ixxoxouia. n. (pret. onixxoxouiac.) pararseme descolorido el rostro por enfermedad.
Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 48v. col. 2. Thanks to Joe Campbell for providing the transcription.