nepololiztli.

Headword: 
nepololiztli.
Principal English Translation: 

perdition or destruction of oneself (see Molina), suicide (see attestations)

IPAspelling: 
nepololistɬi
Alonso de Molina: 

nepololiztli. perdicion o destruicion desi mesmo.
Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 69r. col. 2. Thanks to Joe Campbell for providing the transcription.

Attestations from sources in English: 

See an image that represents nepololiztli in the Visual Lexicon of Aztec Hieroglyphs, ed. Stephanie Wood (Eugene, Ore.: Wired Humanities, 2020-present).

nepololiztli = suicide
Gran Diccionario Náhuatl, citing Wimmer 2004, https://gdn.iib.unam.mx/diccionario/nepololiztli/57622

See also: 
poloa.
-liztli.