a large worry, anxiety and affliction from the heart or a grand anger and sorrow
IPAspelling:
nejoːlellelɑhʃiːtilistɬi
Alonso de Molina:
neyolellelaxitiliztli. angustia y aflicion grande del corazon, o gran enojo y pena. Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 66r. col. 1. Thanks to Joe Campbell for providing the transcription.