a person who is stupid, dazed, stunned (see Molina and dictionaries of American Spanish)
Orthographic Variants:
ayoui pozonini
Alonso de Molina:
ayoui pozonini. apitunado y supito. Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 3v. col. 2. Thanks to Joe Campbell for providing the transcription.