a fatigue and feeling of being afflicted in one's spirit (see Molina)
Alonso de Molina:
cuecuechmiquiliztli. fatiga tal. Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 25v. col. 1. Thanks to Joe Campbell for providing the transcription.