a gold miner (see Molina); or (given the -yan locative suffix), a place where (yellow) gold mining occurs?
Orthographic Variants:
cuztic
Alonso de Molina:
cuztic teocuitlaquixtiloyan. minero de oro. Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 27v. col. 2. Thanks to Joe Campbell for providing the transcription.