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ixco icpac oninen in totecuiyo dios.

(a loanword from Spanish)

Headword: 
ixco icpac oninen in totecuiyo dios.
Principal English Translation: 

to have disrespected or offended our lord (see Molina)
(partly a loanword from Spanish, dios, God)

Alonso de Molina: 

ixco icpac oninen in totecuiyo dios. desacate y ofendi a nuestro señor dios.
Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 45r. col. 1. Thanks to Joe Campbell for providing the transcription.