one whose eyes ache from too much reading (see Molina)
Orthographic Variants:
ixquaquauhtic
Alonso de Molina:
ixquaquauhtic. el que tiene dolor de ojos assi. Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 47r. col. 1. Thanks to Joe Campbell for providing the transcription.