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ixtlatzihuiliztli.

Headword: 
ixtlatzihuiliztli.
Principal English Translation: 

a tiredness from too much reading (see Molina)

Orthographic Variants: 
ixtlatziuiliztli
IPAspelling: 
iʃtɬɑtsiwilistɬi
Alonso de Molina: 

ixtlatziuiliztli. cansancio tal.
Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 48v. col. 1. Thanks to Joe Campbell for providing the transcription.