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mixpopoloa.

Headword: 
mixpopoloa.
Principal English Translation: 

for a community to destroy itself or become ruined (see Molina)

Alonso de Molina: 

mixpopoloa. (pret. omixpopolo) destruirse el pueblo.
Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 57r. col. 2. Thanks to Joe Campbell for providing the transcription.