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nohuehuepo.

Headword: 
nohuehuepo.
Principal English Translation: 

someone who is older, such as I am, or my compadre, or my comadre (see Molina)

Orthographic Variants: 
noueuepo
Alonso de Molina: 

noueuepo. el que es viejo como yo, o mi compadre, o mi comadre.
Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 74r. col. 2. Thanks to Joe Campbell for providing the transcription.