something that torments and greatly afflicts the heart (see Molina)
Alonso de Molina:
teyolcuitlatzayan. cosa que atormenta y aflige mucho el corazon. Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 94v. col. 2. Thanks to Joe Campbell for providing the transcription.