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iyo.

Headword: 
iyo.
Principal English Translation: 

dolorous interjection (see Karttunen)

Orthographic Variants: 
iyoh
IPAspelling: 
iyoh
Alonso de Molina: 

iyo. guay. interjection.
Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 36v. col. 2. Thanks to Joe Campbell for providing the transcription.

Frances Karttunen: 

IYOH dolorous interjection / guay interjección (M) ((I)Bf.8v,(1)Rp.97). The glottal stop is attested only in R.
Frances Karttunen, An Analytical Dictionary of Nahuatl (Norman: University of Oklahoma Press, 1992), 123.

themes: 
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