mayecuele.

Headword: 
mayecuele.
Principal English Translation: 

let it be that .. on with …; a compound introductory particle for clauses expressing strong wishes and exhortations (see Karttunen)

Orthographic Variants: 
māyecuēleh, macuele
IPAspelling: 
mɑːyekweːleh
Alonso de Molina: 

mayecuele. lo mismo es que macuele. aduerbio.
Alonso de Molina, Vocabulario en lengua castellana y mexicana y mexicana y castellana, 1571, part 2, Nahuatl to Spanish, f. 51v. col. 1. Thanks to Joe Campbell for providing the transcription.

Frances Karttunen: 

MĀYECUĒLEH compound introductory particle for clauses expressing strong wishes and exhortations let it be that .. on with … / ojalá (C) [(1)Cf. 26V]. M gloss this as synonymous with MĀCUĒLEH.
Frances Karttunen, An Analytical Dictionary of Nahuatl (Norman: University of Oklahoma Press, 1992), 141.