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popoxon.

Headword: 
popoxon.
Principal English Translation: 

smallpox (See Karttunen)

Orthographic Variants: 
pohpoxōn
IPAspelling: 
pohpoʃoːn
Frances Karttunen: 

POHPOXŌN smallpox / viruela (Z) [(2)Zp.130,183]. In one of the attestations Z marks the vowel of the second syllable long. This appears to be related to POHPOXOĀ 'to turn something over' and implies *POHPOXŌN(I). M's puxactic 'something spongy' may also be relevant.
Frances Karttunen, An Analytical Dictionary of Nahuatl (Norman: University of Oklahoma Press, 1992), 201.

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