Principal English Translation:
to have a fever; to be burning hot
Fr. Bernardino de Sahagún, Florentine Codex: General History of the Things of New Spain; Book 10 -- The People, No. 14, Part 11, eds. and transl. Arthur J. O. Anderson and Charles E. Dibble (Santa Fe and Salt Lake City: School of American Research and the University of Utah, 1961), 159.
Attestations from sources in English:
See an image that represents motlehuia in the Visual Lexicon of Aztec Hieroglyphs, ed. Stephanie Wood (Eugene, Ore.: Wired Humanities, 2020-present).
Motlevia: conj chichipili inelhoaio, chichicaqujlitl, tececec, xocoatl = Fever: One drinks [an infusion of the root of] chichipilli, [with] alum [and] acid water. (central Mexico, sixteenth century)
Fr. Bernardino de Sahagún, Florentine Codex: General History of the Things of New Spain; Book 10 -- The People, No. 14, Part 11, eds. and transl. Arthur J. O. Anderson and Charles E. Dibble (Santa Fe and Salt Lake City: School of American Research and the University of Utah, 1961), 159.