to take charge of something, to take responsibility for something and be accountable for it (see Molina); in the transitive, to blame; in the passive, could refer to being given the responsibility of telling the truth under questioning, under oath
the root of this plant was used to treat a pressure in the chest related to anxiety
Martín de la Cruz, Libellus de medicinalibus indorum herbis; manuscrito azteca de 1552; segun traducción latina de Juan Badiano; versión española con estudios comentarios por diversos autores (Mexico: Fondo de Cultural Económica; Instituto Mexicano del Seguro Social, 1991), 41 [27r].